
Why Berberine.
AMPK activation for metabolic regulation
Blood glucose and HbA1c reduction
Lipid-lowering effects
Gut microbiome support
About Berberine.
Berberine is a bioactive alkaloid extracted from several plants with centuries of use in traditional medicine. It activates AMPK (the "metabolic master switch"), improves insulin sensitivity, lowers blood glucose and lipids, and supports gut microbiome health. Often called "nature's metformin" for its overlapping mechanisms.
How it works.
From intake to your first dose — four straightforward steps.
Complete intake
A brief health questionnaire reviewed by our clinical team. Takes about 5 minutes.
Provider review
A board-certified clinician reviews your history within 48 hours.
Compounded & shipped
Your prescription is compounded in a licensed US pharmacy and shipped to your door.
Ongoing support
Telehealth follow-up to adjust your protocol as needed.
Ready to start Berberine?
Complete a brief health intake and a licensed provider will review your request within 48 hours. No commitments.
All prescriptions are issued at the sole discretion of licensed providers. Protocol Health Rx does not guarantee prescription approval.