
Why MOTS-c.
Mitochondrial-nuclear signaling
Enhanced glucose metabolism
Exercise performance and endurance
Anti-obesity and longevity effects
About MOTS-c.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide that regulates nuclear gene expression involved in metabolism. It enhances glucose uptake, reduces fat accumulation, and protects against metabolic and age-related diseases by acting as a mitochondrial signal to the nucleus.
How it works.
From intake to your first dose — four straightforward steps.
Complete intake
A brief health questionnaire reviewed by our clinical team. Takes about 5 minutes.
Provider review
A board-certified clinician reviews your history within 48 hours.
Compounded & shipped
Your prescription is compounded in a licensed US pharmacy and shipped to your door.
Ongoing support
Telehealth follow-up to adjust your protocol as needed.
Ready to start MOTS-c?
Complete a brief health intake and a licensed provider will review your request within 48 hours. No commitments.
All prescriptions are issued at the sole discretion of licensed providers. Protocol Health Rx does not guarantee prescription approval.